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Faculty Member
Saraswathy Nair, Assistant Professor
The University of Texas Health Science Center - School of Public Health
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Education
| Kerala University (India) |
B.Sc. |
1983 |
Zoology |
| Annamalai University (India) |
M.Sc. |
1985 |
Marine Biology |
| State University of New York at Buffalo |
M.A. |
1987 |
Cell and Molecular Biology |
| State University of New York at Buffalo |
Ph.D. |
1992 |
Cell and Molecular Biology |
Marion Bessin Liver Research Center,
Albert Einstein College of Medicine |
Postdoc
training |
1992-1996 |
Cell and Molecular Biology |
Positions and Employment
| 2006 - present |
Assistant Professor, Department of Biological Sciences, University of Texas at Brownsville/Texas Southmost College, Brownsville, TX |
| 2001 -2006 |
Research fellow, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Phoenix, AZ |
| 2001 |
Adjunct faculty, Glendale Community College, AZ |
| 1996 - 1998 |
Director R & D, Verigen, Inc., Scottsdale, AZ |
| 1992 - 1996 |
Research Associate, Albert Einstein College of Medicine, N.Y. |
| 1986 - 1992 |
Research and teaching assistant, S.U.N.Y. at Buffalo, N.Y. |
Awards and Memberships
| 2005 - present |
Member, American Society of Human Genetics |
| 2001 - 2004 |
Intramural research training award, NIDDK, NIH |
| 1990 - 1996 |
Member, American Society of Cell Biology |
| 1992 - 1995 |
Postdoctoral training award, Marion Bessin Liver Research Center, Albert Einstein College of Medicine |
Publications
- S. Nair, R. Dey, J.P. Sanford and D. Doyle. 1992. Molecular cloning and analysis of an eIF-4A related rat liver nuclear protein. J. Biol. Chem. 267, 12928-35.
- S. Nair, C. Guerra and P. Satir. 1999. A Sec7-related protein in Paramecium. FASEB J., 12, 1249-57.
- R. Lindsay, D. Walker, S. Nair, J. Bunt, D.E.W. Livingstone, P. Permana, P.A. Tataranni, B.R. Walker. 2003. Subcutaneous adipose 11beta-hydroxysteroid dehydrogenase type 1 activity and mRNA levels are associated with adiposity and insulinemia in Pima Indians and Caucasians. J.Clin.Endo.Metab. 88, 2738-44.
- P. Permana, S. Nair, Y.H. Lee, G. Luczy-Bachman, B. Vozarova, P.A. Tataranni. 2004. Subcutaneouos preadipocyte differentiation in vitro is blunted in centrally obese subjects. Am.J.Physiol.Endocrinol.Metab. 286, E958-62
- S. Nair, Y.H. Lee, R. LIndsay, B. Walker, P.A. Tataranni, C. Bogardus, L. Baier and P. Permana. 2004. The 11beta-hydroxysteroid dehydrogenase type 1 gene: Genetic polymorphisms are associated with type 2 diabetes in Pima Indians, iindependent of obesity and expression in adipocyte and muscle. Diabetologia, 47, 1088-95.
- P. Franks, W. Knowler, S. Nair, J. Koska, Y.H. Lee, R. Lindsay, B. Walker, P. Permana, P.A. Tataranni and R. Hanson. 2004. Interaction between an 11beta HSD1 gene variant and birth era modifies the risk of hypertension in Pima Indians. Hypertension, 44, 681-88.
- I.J. Deary, C. Hayward, P.A. Permana, S. Nair, L. Whalley, J.M. Starr, K.E. Chapman, B.R. Walker, J.R. Seckl. 2006. Polymorphisms in the gene encoding 11B-hydroxysteroid dehydrogenase type 1 (HSD11B1) and lifetime cognitive change. Neuroscience Letters, 393, 74-77.
- Y.H. Lee, S. Nair, E. Rousseau, D. Allison, G. Page, C. Bogardus and P. Permana. 2005. Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes. Diabetologia, 48, 1776-1783.
- S. Nair, Y.H. Lee, E. Rousseau, M. Cam, P.A. Tataranni, L. Baier, C. Bogardus and P. Permana. 2005. Increased expression of inflammation-related genes in cultured preadipocytes/stromal vascular cells from obese compared with non-obese Pima Indians. Diabetologia, 48, 1784-1788.
- J. Koska, B. de Courten, D. Wake, S. Nair, B. Walker, J. Bunt, P. Permana, R. Linday, P.A. Tataranni. 2006. Prospective effect of adipose tissue 11beta-hydroxysteroid dehydrogenase type 1 activity and expression on body weight, body composition and insulin resistance. Obesity Research, in press.
- M.T. Traurig, S. Nair, S. Kobes, C. Bogardus and L.J. Baier. 2006. "Differential Expression of Matrix Metalloproteinase 3 (MMP3) in Preadipocytes/SVCs from Non-Obese, Non-Diabetic versus Obese, Non-Diabetic Pima Indians." Diabetes, in press.
Research Support
Completed Support
| NIDDK/NIH - Intramural funds |
08/15/2001 - 05/26/2006 |
Investigating the genetic basis of obesity and Type 2 diabetes mellitus (T2DM) in Pima Indians of Arizona
The main goals of this study were to evaluate gene expression differences between non-obese and obese Pima Indians and genotype variations in candidate genes in a large cohort of Pima Indians, in order to understand the correlations between genetic variation and susceptibility to obesity and T2DM.
Role: Co-investigator |
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